High-Concentration Capsaicin Patch (8%): A Solution for Neuropathic Pain

The 8% capsaicin patch is an innovative option for the treatment of
peripheral neuropathic pain. By acting directly on the nerve fibers responsible for
pain, this treatment offers lasting relief for a variety of conditions.

Main indications :

#1. Peripheral neuropathic pain (PNP)

  • Used alone or as a complement to other medications.

#2. Postherpetic neuralgia (PHN)

  • Specifically approved in the United States to relieve the chronic pain associated with shingles.

#3. Diabetic peripheral neuropathy (DPN)

  • Fast, lasting relief from diabetes-related neuropathic pain.

#4. Post-Surgical Neuropathic Pain (PSNP)

  • Indicated for chronic pain after certain surgical procedures, especially chronic pain following knee, shoulder, hip or other osteosynthesis surgery.
  • Indicated for neuropathic pain following breast cancer surgery.

#5. Chemotherapy-induced neuropathy (CIPN)

  • Promising potential for reducing neuropathic pain associated with cancer treatments, particularly breast cancer.

Mechanism of Action

The capsaicin patch targets nociceptive nerve fibers. It causes a temporary “defunctionalization” of nerve endings, reducing sensitivity and pain. This process is reversible, and the nerve fibers gradually recover.

Advantages :

  • Prolonged relief: a single application can provide weeks of comfort.
  • Favorable safety profile: localized, generally mild and transient side effects.
  • Non-systemic: acts directly on the painful area without any major impact on the rest of the body.
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Side Effects :

Adverse reactions include:

  • Redness and skin irritation at application site.
  • Sensation of heat or transient burning.

These symptoms usually disappear rapidly without intervention.

Conclusion

The 8% capsaicin patch is an effective, well-tolerated solution for relieving peripheral neuropathic pain.

It is particularly recommended for conditions such as postherpetic neuralgia, diabetic neuropathy and pain following prosthetic surgery. If you suffer from neuropathic pain, talk to your doctor to find out if this treatment is right for you.

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Dr Nabila

- Médecin anesthésiste - Spécialiste de la douleur

- Médecin anesthésiste - Spécialiste de la douleur

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