
Pain treatment with ketamine infusion
what you need to know :
Ketamine, long used in the management of chronic intractable pain, is an innovative treatment for reducing nociceptive and neuropathic pain thanks to its powerful antihyperalgesic effect.
How does ketamine work?
Ketamine acts by blocking NMDA receptors, thus “resetting” pain modulation systems. This reduces central hypersensitivity and offers significant relief in pathologies such as :
- Fibromyalgia
- Neuropathic pain
- Ehler-Danlos syndrome
- Migraine with aura



What to expect during treatment
- Duration: 4 to 5 hours in day hospital.
- Regular monitoring by a nurse (blood pressure, side effects).
- Possible side effects, such as drowsiness, strange dreams or double vision, are managed on site.
Expected results :
- Infusion can reduce pain by 30%, with effects lasting from 2 to 6 months in 80% of cases.
Questions Possible side effects :
- Dizziness, headaches
- Psychodysleptic disorders
- Mild hypertension
These effects are rapidly managed by the medical team
Conditions and contraindications:
Treatment is contraindicated in patients with a history of stroke or hypersensitivity to ketamine.
Particular caution is required for conditions such as epilepsy or intracranial hypertension.
Important!
- Arrange for someone to accompany you home.
- Inform your doctor if you are pregnant or if you are taking substances that may interact with ketamine.
If you have any questions or require further information, please do not hesitate to consult your doctor.
This text has been simplified and adapted for a non-specialist audience. If you wish to make any adjustments, let me know in the comments.
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Dr Nabila
- Médecin anesthésiste - Spécialiste de la douleur
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